The 2015 Human Health Assessment Report follows three previous AMAP assessments on human health (AMAP 1998, 2003, 2009) and represents the current knowledge base after 25 years of focused study. This report includes new knowledge, updates and fills information gaps identified in past reports, and focuses attention on the most recent integrated scientific knowledge related to environmental contaminants and human health. It does not update information concerning the levels and effects of radioactivity and UV-radiation; these topics were addressed in the first comprehensive AMAP Assessment Report (AMAP 1998). The AMAP 2015 collects and discuss all the data from the relevant cohorts and surveys carried out in Inuits groups of Alaska, Canada and Greenland. It describes the projects, the results as the levels of contaminants found in the areas, the health that these contaminants can cause, future risks, and risk communication.